Table 1.
The formulations F1–F7 design and composition.
| Ingredients | %w/w | ||||||
|---|---|---|---|---|---|---|---|
| F1 | F2 | F3 | F4 | F5 | F6 | F7 | |
| 5-fluorouracil | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| HPMC | 0.05 | 2.0 | 0.05 | 2.0 | 0.05 | 0.2 | 0.05 |
| Triethanolamine | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 | 0.02 |
| Light liquid paraffin | 3.5 | 2.65 | 3.5 | 2.65 | 3.5 | 2.65 | 3.5 |
| Tween 20 | 0.5 | 0.3 | 0.3 | 0.3 | 0.5 | 0.5 | 0.5 |
| Propylene glycol | 3.5 | 3.5 | 3.5 | 3.5 | 3.5 | 3.5 | 3.5 |
| Sodium benzoate | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 | 0.5 |
| Ethanol | 1.55 | 1.55 | 1.55 | 1.55 | 1.55 | 1.55 | 1.55 |
| Eucalyptus oil | 1 | 5 | - | - | - | 5 | 1 |
| Clove oil | - | - | 1 | 5 | - | 1 | 5 |
| Purified water (q.s) | 50 | 50 | 50 | 50 | 50 | 50 | 50 |