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. 2023 Mar 15;14(3):717. doi: 10.3390/genes14030717

Figure 2.

Figure 2

(A–D) Harlequin ichthyosis in patient 36. (A) Generalized dry and red scaly skin on the back, (B) palmoplantar hyperkeratosis, (C) joint contractures at fingers and thickened fingernails, and (D) face with red, scaly skin, ectropion, and hypoplastic ears. (E) Harlequin ichthyosis in patient 26 at the day of birth. Large thick plates separated by deep cracks. Ectropion, eclabion, hypoplastic nose and ears. (F–H) Lamellar ichthyosis in patient 48. (F) Palmoplantar hyperkeratosis, (G) ichthyotic skin on the neck, and (H) skin with large dark scales and contractures of fingers. (I–L) Congenital ichthyosiform erythroderma in patient 26. (I) Thickened skin with white scales in a newborn, (J) erythroderma of the palms, (K) generalized erythroderma with fine white scales, and (L) palmoplantar hyperkeratosis.