Table 2.

Experimental design and results of response surface methodology.

Run	Variables				TPC (Y1)	TFC (Y2)
	X1 (%)	X2 (°C)	X3 (min)	X4 (W)	(mg FAE/g DW)	(mg RE/g DW)
1	10	40	40	300	6.65 ± 0.04	3.60 ± 0.03
2	20	40	40	300	6.70 ± 0.05	3.66 ± 0.02
3	10	60	40	300	6.76 ± 0.01	3.68 ± 0.02
4	20	60	40	300	6.80 ± 0.02	3.67 ± 0.01
5	15	50	30	250	6.66 ± 0.03	3.57 ± 0.05
6	15	50	50	250	6.78 ± 0.02	3.66 ± 0.01
7	15	50	30	350	6.72 ± 0.01	3.58 ± 0.04
8	15	50	50	350	6.80 ± 0.03	3.79 ± 0.02
9	10	50	40	250	6.63 ± 0.03	3.60 ± 0.01
10	20	50	40	250	6.70 ± 0.01	3.62 ± 0.03
11	10	50	40	350	6.73 ± 0.05	3.66 ± 0.03
12	20	50	40	350	6.80 ± 0.02	3.68 ± 0.01
13	15	40	30	300	6.59 ± 0.01	3.58 ± 0.02
14	15	60	30	300	6.73 ± 0.06	3.61 ± 0.01
15	15	40	50	300	6.75 ± 0.04	3.66 ± 0.01
16	15	60	50	300	6.83 ± 0.02	3.73 ± 0.02
17	10	50	30	300	6.71 ± 0.03	3.63 ± 0.01
18	20	50	30	300	6.53 ± 0.02	3.69 ± 0.03
19	10	50	50	300	6.76 ± 0.01	3.72 ± 0.01
20	20	50	50	300	6.86 ± 0.04	3.78 ± 0.06
21	15	40	40	250	6.61 ± 0.01	3.57 ± 0.02
22	15	60	40	250	6.80 ± 0.03	3.67 ± 0.01
23	15	40	40	350	6.79 ± 0.10	3.70 ± 0.03
24	15	60	40	350	6.81 ± 0.01	3.74 ± 0.02
25	15	50	40	300	7.30 ± 0.01	4.11 ± 0.01
26	15	50	40	300	7.29 ± 0.02	4.23 ± 0.03
27	15	50	40	300	7.21 ± 0.05	3.92 ± 0.02
28	15	50	40	300	7.21 ± 0.01	4.32 ± 0.02
29	15	50	40	300	7.11 ± 0.01	4.31 ± 0.02