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. 2023 Mar 12;24(6):5419. doi: 10.3390/ijms24065419

Figure 2.

Figure 2

MPE and MSE counteract PA-induced toxicity in 3T3-L1 adipocytes. Differentiated 3T3-L1 adipocytes were exposed for 48 h to different doses of PA alone or in the presence of 100 μg/mL MPE and MSE. (A) MTT assays showing the reduction of cell viability induced in differentiated 3T3-L1 adipocytes by different doses of PA. (B) MTT assays showing the ability of 100 µg/mL of MPE or MSE to counteract the cytotoxic effect of 500 µM PA in differentiated 3T3-L1 adipocytes. (C) Representative phase contrast microscopy images showing the morphological changes induced by 500 µM PA alone or in the presence of 100 µg/mL MPE or MSE in differentiated 3T3-L1 adipocytes. (A,B) The values reported are the mean ± SD of three independent experiments. The statistical differences between groups were evaluated using a one-way ANOVA test. * p < 0.05, ** p < 0.01 and *** p < 0.001 were significant with respect to differentiated 3T3-L1 adipocytes treated with only vehicle BSA.