. 2023 Mar 9;24(6):5224. doi: 10.3390/ijms24065224

Table 3.

Impact of A. paniculata on the overall number of ACF in the colon.

Group	No. of Crypts per ACF					Total No. of ACF/Colon
Group	One Crypt	Two Crypts	Three Crypts	Four Crypts	Five or More Crypts	Total No. of ACF/Colon
N	0	0	0	0	0	0
NC	5.25 ± 1.60 ^ab	3.50 ± 0.90 ^a	1.50 ± 0.70 ^a	1.62 ± 0.56 ^ab	3.25 ± 1.08 ^a	15.37 ± 0.26 ^ab
H	1.37 ± 0.73 ^b	2.00 ± 0.94 ^a	3.50 ± 0.56 ^a	2.25 ± 0.45 ^ab	6.12 ± 1.67 ^ab	15.12 ± 0.12 ^ab
HC	7.50 ± 1.42 ^a	3.87 ± 0.63 ^a	1.62 ± 0.46 ^a	0.87 ± 0.35 ^b	6.50 ± 1.50 ^ab	20.37 ± 0.80 ^c
HCF	5.87 ± 1.41 ^ab	1.87 ± 0.63 ^a	2.00 ± 0.82 ^a	0.37 ± 0.18 ^b	7.25 ± 1.94 ^ab	17.62 ± 0.37 ^d
HCAP125	2.80 ± 1.15 ^ab	1.80 ± 0.58 ^a	1.00 ± 0.31 ^a	0.60 ± 0.40 ^b	10.80 ± 0.86 ^b	17.00 ± 0.83 ^ad
HCAP250	1.16 ± 0.47 ^b	2.66 ± 0.71 ^a	3.83 ± 0.70 ^a	3.50 ± 0.76 ^a	5.16 ± 0.83 ^ab	16.33 ± 0.33 ^abd
HCAP500	5.00 ± 1.69 ^ab	1.66 ± 0.33 ^a	1.66 ± 0.33 ^a	1.16 ± 0.98 ^ab	4.33 ± 1.72 ^ab	13.83 ± 0.87 ^b

The data are given as mean ± SE. Mean values with distinct alphabetical letters in the same column were significantly different at p < 0.05 (ANOVA, Tukey’s post hoc). N, normal diet; NC, normal diet + DMH; H, HFD; HC, HFD + DMH; HCF, HFD + DMH + 5-FU; HCAP125, HFD + DMH + 125 mg/kg A. paniculata ethanol extract; HCAP250, HFD + DMH + 250 mg/kg A. paniculata ethanol extract; HCAP500, HFD + DMH + 500 mg/kg A. paniculata ethanol extract.