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. 2023 Mar 9;24(6):5238. doi: 10.3390/ijms24065238

Table 2.

Summary of the susceptibility biomarkers implicated in PTSD.

Susceptibility Biomarker Findings
Number of GR in lymphocytes and monocytes A higher number pre-trauma of GR is associated with high PTSD symptoms in soldiers after deployment [175].
Sensitivity of T cells to dexamethasone before deployment High sensitivity pre-trauma is associated with a high amount of PTSD symptoms without comorbid depressive symptoms. Different sensitivity patterns are associated with different symptomatology [176].
mRNA levels of FKBP5 Low levels after deployment are associated with a high amount of PTSD symptoms [176].
Glucocorticoid-induced leucine zipper mRNA High levels pre-trauma are associated with a high amount of PTSD symptoms post-deployment [177].
Corticotropin-releasing hormone type 1 receptor gene Polymorphisms were associated with PTSD development [178].
Heart rate Increased heart rates in the post-traumatic period were associated with PTSD development [179].
Occurrence of Nightmares Higher occurrence of nightmares pre-trauma was associated with disease susceptibility in Dutch combat soldiers [180].
Increased skin conductance Skin conductance response (SCR) within hours of trauma exposure was a predictor of chronic PTSD development [181].