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. 2023 Mar 9;24(6):5241. doi: 10.3390/ijms24065241

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Histological changes in the hearts of the diabetic rats. (A) Cardiac hypertrophy: representative images of histological cross sections stained with periodic acid–Schiff in (A1) control and (A2) diabetic rats, and (A3) relative quantification of cardiomyocyte size. (B) Cardiac fibrosis: representative images of histological sections stained with Picrosirius Red in (B1) control and (B2) diabetic rats, and (B3) percentage of cardiac fibrosis. Non-parametric Wilcoxon rank sum test was used. Horizontal line represents median. *** p < 0.001 vs. control.