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Schematic illustration of the glucose-responsive supramolecular insulin delivery system. (a) Chemical structure and the mechanism of the multiresponsive diphenylboronic acid guest G. (b) Supramolecular self-assembly of the host–guest complex “P5A6*G” into vesicles and their successful encapsulation of insulin and GOx as well as the efficient insulin release under hyperglycemic state. Reproduced from reference [108]. Copyright © Wiley 2018.
