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Structures of bedaquiline (BDQ) and TBAJ-876. In TBAJ-876, BDQ’s quinoline (A) and dimethylamino (D) groups are retained, whereas its phenyl (B) and naphthalene (C) groups are replaced with 2,3,5-trialkoxypyridin-4-yl and 3,5-dialkoxypyridin-4-yl groups, respectively. Reprinted from Sarathy et al. [122] under the terms of the Creative Commons Attribution 4.0 International Public License.
