Table 2.
Cluster 1 | Cluster 2 | Cluster 3 | |
---|---|---|---|
Number of AIS episodes | 9116 | 13,330 | 6825 |
Average number of AIS per day | 13 | 13 | 15 |
Entire cohort | 1.00 | 0.98 (0.95–1.00) | 1.09 (1.05–1.13) b,c |
Subgroups | |||
Age | |||
<65 years | 1.00 | 1.01 (0.97–1.05) | 1.06 (1.01–1.12) b,c |
≥65 years | 1.00 | 0.95 (0.92–0.99) a | 1.12 (1.07–1.17) b,c |
Gender | |||
Male | 1.00 | 0.98 (0.94–1.02) | 1.08 (1.04–1.14) b,c |
Female | 1.00 | 0.97 (0.93–1.01) | 1.10 (1.05–1.16) b,c |
Ethnicity | |||
Chinese | 1.00 | 0.95 (0.92–0.99) a | 1.09 (1.05–1.14) b,c |
Malay | 1.00 | 1.00 (0.95–1.06) | 1.05 (0.98–1.12) |
Indian | 1.00 | 1.04 (0.98–1.10) | 1.03 (0.96–1.10) |
History of stroke/TIA | |||
Yes | 1.00 | 0.96 (0.91–1.01) | 1.05 (0.99–1.12) |
No | 1.00 | 0.98 (0.93–1.03) | 1.07 (1.01–1.14) b,c |
History of IHD/AF/VHD/PVD | |||
Yes | 1.00 | 0.92 (0.88–0.97) a | 1.07 (1.02–1.14) b,c |
No | 1.00 | 1.02 (0.97–1.07) | 1.15 (1.09–1.22) b,c |
History of diabetes | |||
Yes | 1.00 | 1.00 (0.96–1.04) | 1.10 (1.05–1.16) b,c |
No | 1.00 | 0.98 (0.94–1.03) a | 1.12 (1.06–1.19) b,c |
History of hypertension | |||
Yes | 1.00 | 0.96 (0.93–0.99) a | 1.09 (1.04–1.13) b,c |
No | 1.00 | 1.01 (0.96–1.07) | 1.04 (0.98–1.11) |
History of hyperlipidaemia | |||
Yes | 1.00 | 0.95 (0.92–0.99) a | 1.10 (1.05–1.15) b,c |
No | 1.00 | 1.00 (0.95–1.06) | 1.07 (1.00–1.13) b,c |
Current/former smoker | |||
Yes | 1.00 | 0.98 (0.94–1.03) | 1.05 (1.00–1.11) b,c |
No | 1.00 | 0.96 (0.93–1.00) | 1.12 (1.07–1.17) b,c |
a Significant difference in IRR between Cluster 1 and Cluster 2 (p < 0.05). b Significant difference in IRR between Cluster 1 and Cluster 3 (p < 0.05). c Significant difference in IRR between Cluster 2 and Cluster 3 (p < 0.05). Poisson regression test was used to obtain the p-values. AIS: acute ischaemic stroke; IQR: interquartile range; TIA: transient ischaemic attack; IHD: ischaemic heart disease; AF: atrial fibrillation; VHD: valvular heart disease; PVD: peripheral vascular disease. The bolded represents a significant difference in the IRR.