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. 2023 Mar 12;24(6):5436. doi: 10.3390/ijms24065436

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The miRNAs potentially implicated in hematopoiesis and leukemogenesis. (A) Hematopoiesis process is schematized, and examples of miRNAs expressed involved in the cell differentiation and maturation are indicated. (B) The miRNAs with dysregulated expression that are potentially involved in oncogenic lymphoblast transformation and progression are shown. MiRNAs in red means downregulation, and miRNAs in green means upregulation; HSCs, hematopoietic stem cells; MPP, multipotent progenitors; CLP, common lymphoid progenitors; CMP, common myeloid progenitors; CFU-G, granulocytic colony-forming unit.