7. Effects of angiotensin converting enzyme inhibitors (ACEi) versus other classes of antihypertensive medication.
Outcome | Trial identifier | Comparator class | RR (95% CI) |
Incidence of DR | DEMAND | ACEi + CCB | 0.48 (0.13, 1.86) |
Progression of DR | UKPDS/HDS | Beta blocker | 1.01 (0.75, 1.35) |
Combined incidence and progression of DR | ABCD (1) | CCB | 1.33 (0.93, 1.92) |
ABCD (2) | CCB | 0.93 (0.71, 1.21) | |
RASS | ARB | 0.89 (0.49, 1.87 | |
Regression of DR | BENEDICT | Non‐ACEi | 0.44 (0.22, 0.87) |
All‐cause mortality | UKPDS/HDS | Beta blocker | 0.88 (0.64, 1.20) |
ACEi, angiotensin‐converting enzyme inhibitor ARB, angiotensin receptor blocker CCB, calcium channel blocker DR, diabetic retinopathy RR, risk ratio CI, confidence interval