Table 4.

Regions of significant grey matter intensity decrease common to (a) emotional apathy and social reward learning, (b) emotional apathy and monetary reward learning, (c) social reward learning and monetary reward learning, and (d) emotional apathy, social reward learning and monetary reward learning

Regions		Peak MNI coordinates
	Hemisphere	X	Y	Z	Cluster size
(a) Emotional apathy and social reward learning
Orbitofrontal cortex, nucleus accumbens, putamen, insular cortex	L	−22	14	−14	542
Inferior frontal gyrus	R	58	10	2	288
Middle frontal gyrus	L	−26	−2	46	228
Inferior temporal gyrus (anterior)	R	42	0	−40	198
Orbitofrontal cortex, frontal pole	R	40	34	−8	160
Middle temporal gyrus (posterior)	R	58	−18	−20	111
(b) Emotional apathy and monetary reward learning
Nucleus accumbens	L	−2	2	−12	226
Middle temporal gyrus (posterior)	R	70	−16	−24	162
Middle temporal gyrus (posterior)	L	−44	−40	2	123
Superior temporal gyrus (planum temporale)	L	−54	−32	16	109
(c) Social reward learning and monetary reward learning
Nucleus accumbens, putamen, caudate (left), orbitofrontal cortex (left), insular cortex (left)	B	0	4	−14	1143
Inferior frontal gyrus	R	40	18	16	258
Central opercular cortex	L	−36	−18	20	187
Frontal pole	L	−16	56	−6	186
Anterior cingulate gyrus	B	6	−10	26	183
Parietal operculum cortex, insular cortex	R	36	−24	16	157
Superior frontal gyrus	L	−12	36	38	157
Occipital pole	R	26	−96	−10	142
(d) Emotional apathy, social reward learning and monetary reward learning
Nucleus accumbens	L	−12	6	−12	177
Amygdala, orbitofrontal cortex, nucleus accumbens	R	24	2	−6	168

Clusters were extracted voxel-wise corrected for false discovery rate at p < 0.05. All clusters reported t > 2.68, with a cluster extent threshold of >100 contiguous voxels.

L = left; R = right; B = bilateral; MNI = Montreal Neurological Institute.