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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Stroke. 2023 Feb 17;54(4):973–982. doi: 10.1161/STROKEAHA.122.041701

Figure 4. MetaGRS and cumulative risk of incident intracerebral hemorrhage (ICH) in the population-based UK Biobank sample.

Figure 4.

The results are derived from (A) entire UKBB population, (B) users of antithrombotic medications at baseline, and (C) low-risk individuals with conventional vascular risk factors under control and no use of anticoagulant medications after excluding prevalent cases of ICH. Depicted are the Kaplan-Meier curves for different metaGRS quantiles, as well as the hazard ratios (HR) per standard deviation (SD) increment in metaGRS, as derived from Cox proportional hazards regression models adjusted for baseline age, sex, the first 10 principal components of the population structure, genetic ancestry, genotyping chip, and kinship.