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. Author manuscript; available in PMC: 2023 Mar 29.
Published in final edited form as: J Alzheimers Dis. 2023;92(2):395–409. doi: 10.3233/JAD-220599

Figure 4. Association of the liver PRS with CSF biomarkers (APOE included).

Figure 4.

The strength of association of the liver PRS (with the APOE locus included) with each CSF biomarker from the linear mixed effects regression models is shown (n range = 245–250 visits). The horizontal lines indicate thresholds for significance, with the black line indicating the nominal threshold of P = 0.05 and the red line indicating the Bonferroni-corrected threshold of P = 0.0056. The liver PRS was statistically significantly associated with the measures of amyloid and tau but not with the other biomarkers.