Table 1.
Baseline demographics and outcomes by smoking stratification.
| Variable* | Never smoker (n=1,152) |
Prior smoker (n=1,152) |
Smoker who quit by month 3 (n=162) |
Persistent smoker at month 3 (n=408) |
P value |
|---|---|---|---|---|---|
|
| |||||
| Age | 64.4±11.1 | 63.9±10.5 | 58.1±8.9 | 57.8±8.9 | <0.001 |
|
| |||||
| Female sex | 610 (53.0%) | 296 (25.7%) | 37 (22.8%) | 117 (28.7%) | <0.001 |
|
| |||||
| Race | <0.001 | ||||
| White | 596 (51.8%) | 683 (59.3%) | 104 (64.2%) | 262 (64.2%) | |
| Black | 150 (13.0%) | 165 (14.3%) | 35 (21.6%) | 106 (26.0%) | |
| Other | 406 (35.2%) | 304 (26.4%) | 23 (14.2%) | 40 (9.8%) | |
|
| |||||
| Hispanic ethnicity | 573 (49.7%) | 475 (41.2%) | 97 (59.9%) | 125 (30.6%) | <0.001 |
|
| |||||
| Education | <0.001 | ||||
| 0-4 years | 167 (14.5%) | 108 (9.4%) | 20 (12.3%) | 17 (4.2%) | |
| 5-8 years | 205 (17.8%) | 168 (14.6%) | 32 (19.8%) | 49 (12.0%) | |
| 9-12 years | 377 (32.7%) | 433 (37.6%) | 79 (48.8%) | 198 (48.5%) | |
| Any college | 403 (35.0%) | 443 (38.4%) | 31 (19.1%) | 144 (35.3%) | |
|
| |||||
| Employed | 649 (56.3%) | 637 (55.3%) | 58 (35.8%) | 183 (44.9%) | <0.001 |
|
| |||||
| Hypertension | 888 (77.1%) | 890 (77.3%) | 97 (60.0%) | 277 (67.9%) | <0.001 |
|
| |||||
| Diabetes | 419 (36.4%) | 390 (33.9%) | 41 (25.3%) | 104 (25.5%) | <0.001 |
|
| |||||
| Hyperlipidemia | 554 (48.1%) | 589 (51.1%) | 64 (39.5%) | 189 (46.3%) | 0.026 |
|
| |||||
| Prior myocardial infarction | 40 (3.5%) | 70 (6.1%) | 4 (2.5%) | 34 (8.3%) | <0.001 |
|
| |||||
| Years smoked | - | 24.0±14.8 | 32.1±14.9 | 35.6±12.1 | <0.001 |
|
| |||||
| Randomized to intensive blood pressure arm | 557 (48.4%) | 582 (50.5%) | 80 (49.4%) | 215 (52.7%) | 0.472 |
|
| |||||
| Systolic blood pressure during follow up (mean (SD)) | 134.7 (14.4) | 134.1 (14.1) | 133.4 (12.3) | 135.1 (14.9) | 0.403 |
|
| |||||
| Days between qualifying event and randomization | 75.5±48.3 | 78.3±46.7 | 70.0±45.5 | 75.5±46.3 | 0.147 |
|
| |||||
| Mean follow-up (months) | 41.7±24.4 | 42.7±24.4 | 38.8±23.5 | 39.4±26.5 | 0.052 |
|
| |||||
| Primary outcome | 164 (14.2%) | 186 (16.2%) | 20 (12.4%) | 75 (18.4%) | 0.133 |
|
| |||||
| Secondary outcomes | |||||
| Stroke | 92 (8.0%) | 97 (8.4%) | 13 (8.0%) | 37 (9.1%) | 0.922 |
| MI | 38 (3.3%) | 36 (3.1%) | 4 (2.5%) | 22 (5.3%) | 0.154 |
| Death | 73 (6.3%) | 88 (7.6%) | 7 (4.3%) | 32 (7.7%) | 0.286 |
Binary variables shown as n (%) and interval variables as mean±SD. Intergroup differences tested with the chi-squared test for binary variables and ANOVA test for interval variables.
*
no missing data.