Table 1.
Middle East respiratory syndrome CoV variants by year of reporting, country, host, clade, and lineage.
| Function | Region | Mutation | Host | Clade | Lineage | Country | Year | Country | Region | Mutation | Host | Year |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| S1 | NTD | Val30Ala | Camels | C | - | Egypt | 2014 | Kenya | NTD | Val30Ala | Camels | 2019 |
| Ethiopia | 2017-2019 | Ap177Tyr | Camels | 2019 | ||||||||
| Val30Phe | Camels | B | 2,4,6,7 | UAE | 2014 | Ser32Pro | Camels | 2019 | ||||
| Ser32Pro | Camels | B | 2,4,6,7 | UAE | 2014-2015 | His215Tyr | Camels | 2019 | ||||
| Thr105Ile | Camels | B | 5 | Jordan | 2016 | |||||||
| Ser143Ala | Humans | B | 4 | Saudi Arabia | 2017 | |||||||
| CTD/RBD | Ser485Thr | Camels | B | 4.7 | UAE | 2015 | CTD/RBD | Ser416Phe | Camels | 2019 | ||
| Phe499Ser | Humans | B | 4 | Saudi Arabia | 2015-2017 | Leu476Phe | Camels | 2019 | ||||
| Ile568Thr | Camels | A | - | Saudi Arabia | 2017 | Pro673Arg | Camels | 2019 | ||||
| Humans | B | 4 | Saudi Arabia | 2017 | ||||||||
| Humans | B | 5 | South Korea | 2015 | ||||||||
| S2 | Loop | Pro758Ser | Camels | B | 5,6,7 | UAE | 2014-2015 | Loop | Ala1218Ser | Camels | 2019 | |
| Leu795Phe | Humans | B | 4 | Saudi Arabia | 2017-2018 | |||||||
| Gln883Arg | Humans | B | 4 | Saudi Arabia | 2014-2015 | |||||||
| UAE | ||||||||||||
| USA | ||||||||||||
| Jordan | ||||||||||||
| HR2 | Gly1276Ser | Camels | B | 3.4 | Saudi Arabia | 2014-2015 | HR1 | Gln1070Arg | Camels | 2019 | ||
| Cytoplasmic | Cys1387Phe | Camels | B | 5 | Saudi Arabia | 2014-2015 |
CTD, C-terminal domain; HR, heptad repeat; NTD, N-terminal domain; RBD, receptor-binding domain.