Table 1.
List of acrolein-modified proteins in kidney tissues of HFD mice identified by LC/MS/MS analysis.
| No. | Protein name | Abbreviation | Amino acid sequence | pI/ MW (Da) |
|---|---|---|---|---|
| 1 | Carboxylesterase 1F | Ces1f | LGGASSFDGR | 6.0/ 59768.9 |
| 2 | Carboxylesterase 1D | Ces1d | DGASEEETNLSK | 6.2/ 59839.4 |
| 3 | Dihydrolipoyl dehydrogenase, mitochondrial | Dld | ADGSTQVIDTK | 6.4/ 50242.7 |
| 4 | Propionyl-CoA carboxylase beta chain, mitochondrial | Pccb | SVTNEDVTQEQLGGAK | 6.5/ 55600.6 |
| 5 | Glutamate dehydrogenase 1, mitochondrial | Glud1 | NLNHVSYGR | 6.7/ 55973.4 |
| 6 | Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial | Aldh6a1 | VCNLIDSGTK+SSFRGDTNFYGK | 7.0/ 54605.8 |
| 7 | Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial | Oxct1 | AGNVIFR | 7.0/ 51843.9 |
| 8 | Pyruvate kinase PKM | Pkm | GSGTAEVELKK | 7.2/ 57808.0 |
| 9 | Catalase | Cat | RFNSANEDNVTQVR | 7.7/ 59626.6 |
| 10 | 14–3-3 protein zeta/delta | Ywhaz | VVSSIEQKTEGAEK | 4.7/ 27771.1 |
| 11 | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenaseactivation protein, beta polypeptide | Ywhab | AVTEQGHELSNEER | 4.9/ 27364.6 |
| 12 | Indolethylamine N-methyltransferase | Inmt | FQHYM*VGPK | 6.0/ 29440.8 |
| 13 | Carbonic anhydrase 2 | Ca2 | IGPASQGLQK | 6.5/ 28901.4 |
| 14 | Bisphosphoglycerate mutase | Bpgm | MALNHGEEQVR | 6.7/ 29828.6 |
| 15 | Persulfide dioxygenase ETHE1, mitochondrial | Ethe1 | LSGAQADLHIGEGDSIR | 6.6/ 27006.7 |
| 16 | Triosephosphate isomerase | Tpi1 | SNVNDGVAQSTR | 7.1/ 26564.7 |
| 17 | Glutathione S-transferase Mu 1 | Gstm1 | ITQSNAILR | 8.1/ 25822.0 |