Table 3.
Comparison between prediction of patient survival based on TCGA dataset and review of published literature.
| Gene ID | Cancer type | Literature reported HR for patients with high level of gene or corresponding protein in the tumors. | TCGA calculated HR for patients with high expression of gene in the tumors | Reference |
|---|---|---|---|---|
| CD44 | Renal cell carcinoma | high | high | (84) |
| CD44 | Low grade glioma | high | high | (85, 86) |
| CD44 | Thyroid | high | low | (87) |
| CXCR4 | Breast | high | low | (88) |
| CXCR4 | Thyroid (CD8 low) |
high | low | (89) |
| CXCR4 | Lung | high | low | (90) |
| ICAM1 | Breast | low | low | (91) |
| ICAM1 | Breast | high | low | (92) |
| CDH1 | Colorectal | low | low | (93, 94) |
| CDH1 | Low grade glioma | high | high | (95) |
| CDH1 | Kidney renal papillary cell carcinoma | high | high | (96) |
| CDH1 | Squamous cell carcinoma | low | low | (97) |
| IL6R | Glioblastoma | high | high | (98) |
| IL6R | Lung adenocarcinoma | low | low | (99, 100) |
| IL6R | Kidney renal clear cell carcinoma | high | low | (101, 102) |
| NOTCH1 | Kidney renal clear cell carcinoma | high | low | (103, 104) |
| NOTCH1 | Low grade glioma | high | low | (105, 106) |
| TGFBR2 | Lung adenocarcinoma | low | low | (107, 108) |
| TGFBR2 | Lung squamous cell carcinoma | low | high | (107, 108) |
| TGFBR2 | Breast cancer | low | high | (109, 110) |
| TGFBR2 | Breast cancer | high | high | (111) |
| EPCAM | Breast cancer | high | low | (112) |
| EPCAM | Low grade glioma | high | low | (113) |
| EPCAM | Kidney renal clear cell carcinoma | low | low | (114) |
| EPCAM | Kidney renal papillary cell carcinoma | low | low | (114) |
| VCAM1 | Kidney renal clear cell carcinoma | low | low | (115, 116) |