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. 2023 Mar 15;15:1132808. doi: 10.3389/fnagi.2023.1132808

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Correlations of serum NFL levels with clinical/neurophysiological indices of UMN and LMN dysfunction. (A) Correlation between sNFL and PUMNS. (B) Correlation between sNFL and LMN score. (C) Correlation between sNFL and composite MRC score. (D) Correlation between sNFL and active spinal denervation score. CI, confidence interval; LMN, lower motor neuron; MRC, Medical Research Council; NFL, neurofilament light chain; PUMNS, Penn Upper Motor Neuron Score; sNFL, serum neurofilament light chain; UMN, upper motor neuron.