Table 2.
Major clinical trials reporting the efficacy of oncolytic virus therapy for the treatment of brain tumors.
| Clinical Trial no. (clinicaltrials.gov.in) | Virus type | Phase | Status | Aim | Ref. |
|---|---|---|---|---|---|
|
NCT03178032 (2022) |
DNX-2401 | I | Active | To assess the safety and adverse-event profile of DNX-2401. | (45) |
|
NCT02457845 (2021) |
G207 | I | Completed | Determine the safety of combining G207 alone or with a single low dose of radiation. | (46) |
|
NCT01491893 (2018) |
PVSRIPO | I | Completed | Determine the MTD and the Recommended Phase 2 Dose of PVSRIPO | (47) |