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. 2023 Mar 15;13:1140277. doi: 10.3389/fonc.2023.1140277

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Copyright © 2023 Huang, Gao, Li, Yang, Jiang, Liao, Luo and Lu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Sonographic images from a 54-year-old man with chronic hepatitis B. A hyperechoic mass measuring 2.8 cm was found in the left lobe of the liver. On SonoVue-enhanced US, the mass showed isoenhancement through all vascular phases without definite washout (A-C, white star). On Sonazoid-enhanced US, the mass was slightly hyperenhanced in the arterial phase (D, white arrow) without obvious washout in either the subsequent vascular phase (E, white star) or defect in the Kupffer phase (F, white star). The lesion was confirmed to be a high-grade dysplastic nodule by histopathology.