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. 2023 Mar 15;13:1140277. doi: 10.3389/fonc.2023.1140277

Table 3.

Comparison of Washout and Kupffer phase features according to contrast agent used.

Variable Late (≥60 s) and Mild Washout Early Washout
(< 60 s)
No Washout Marked Washout
(≤120 s)
Kuppfer Phase Filling defect
Sonovue Sonazoid Sonovue Sonazoid Sonovue Sonazoid Sonovue Sonazoid
HCC (n=55) 44 (80) 41 (74.5) 11 (20) 12 (21.8) 0 (0) 2 (3.6) 1 (1.8) 0 (0) 54 (98.2)
Non-HCC malignancy (n=3) 0 (0) 0 (0) 3 (100) 3 (100) 0 (0) 0 (0) 3(100) 3(100) 3 (100)
Benign lesions (n=4) 0 (0) 0 (0) 0 (0) 0 (0) 4 (100) 4 (100) 0 (0) 0 (0) 3 (75)

Data are numbers of nodules with percentage in parentheses. HCC, hepatocellular carcinoma.