Fig. 4.

qPCR analysis of HPV-16⁺ CaSki cells treated with Notch-1 inhibitor, DAPT for 24 h; a Mock represents solvent control used in preparation of 62.5 mM/L DAPT, a Notch-1 inhibitor. X-axis represents the relative gene expression (fold change) for mock, Notch-1, Hes-1, Hey-1 and EGFR, b Mock represents solvent control used in preparation of 62.5 mM/L DAPT, a Notch-1 inhibitor. X-axis represents the relative gene expression (fold change) for mock, CDK2, cyclin D and p21. (* denotes p ≤ 0.05, the significant difference level)