Table 2.

Cross-sectional association between eGFR and plasma biomarkers^a.

	N	Unadjusted model			Adjusted modelb
		β	95% CI	p	β	95% CI	p
Whole
Aβ42/40	333	0.00	0.00,0.00	0.800	0.00	0.00,0.00	0.198
p-tau181	639	−0.12	−0.23,-0.01	0.040	−0.06	−0.18,0.06	0.312
NfL	638	−0.47	−0.58,-0.36	<0.001	−0.27	−0.38,-0.15	<0.001
A−
Aβ42/40	183	0.00	0.00,0.00	0.339	0.00	0.00,0.00	0.296
p-tau181	295	−0.11	−0.18,-0.03	0.008	−0.09	−0.17,0.00	0.039
NfL	294	−0.47	−0.64,-0.29	<0.001	−0.28	−0.46,-0.09	0.004
A+
Aβ42/40	150	0.00	0.00,0.00	0.414	0.00	0.00,0.00	0.318
p-tau181	344	−0.10	−0.29,0.09	0.296	−0.07	−0.27,0.14	0.521
NfL	344	−0.45	−0.58,-0.32	<0.001	−0.27	−0.40,-0.13	<0.001

^aA⁻ represents Aβ-PET negative sample, A⁺ represents Aβ-PET positive sample. ^bAdjusted for age and sex.