Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Mar 22;20:100614. doi: 10.1016/j.mtbio.2023.100614

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 Published by Elsevier Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 6 — Anti-inflammatory electroconductive hydrogel for Parkinson's disease with self-healing property. a) The self-healing O-carboxymethyl chitosan (CMC)/DAPU/gold nanoparticles (Au-NPs) hydrogels (CDAHs) hydrogels have the capability to be injected with a 30G syringe needle to write letters (internal diameter = 152.4 μm). b) These hydrogels can be used to fill star-shaped molds. c) The atlas of the rat brain indicates the locations of the striatum, substantia nigra pars compacta (SNpc), and immunostaining types. The behavior tests of the PD rats after hydrogel injection for 7 and 14 days; d) the spontaneous circling speed (red arrow: circling direction) and e) the cylinder asymmetry (red arrow: forelimb contact). f) The schematic illustration presents the treatment of the Parkinson's disease rat model by injecting CDAH hydrogels into the damaged regions for 7 and 14 days. The PD was inducted via injecting 6-hydroxydopamine (6-OHDA) into the brain of rats. The efficacy of the hydrogels was assessed with immunofluorescent analyses and behavior tests. g, h) Functional recovery was quantitatively evaluated for the circling speeds and the impaired forelimb contact [216]. Copyright 2022 Elsevier.