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Schedule for different immunization regimens.
| Group | Prime | Boost |
|---|---|---|
| NC | PBS | PBS |
| 2×mRNA | mRNA | mRNA |
| 2×Ad5 | Ad5 | Ad5 |
| Ad5+mRNA | Ad5 | mRNA |
Details of the different prime-boost strategies used to immunize four groups of mice. NC, negative control; PBS, phosphate buffered solution; mRNA, mRNA vaccine; Ad5, replication-defective human type 5 adenovirus-vectored vaccine.
