Figure 9.

Photomicrograph of skin (immune staining) showing TNF-α expression at the wound area, control -ve showed negative expression of TNF-α, control +ve group showed marked TNF-α positive staining, mild TNF-α expression was noticed in standard and nano-S. platensis gel (SPNP-gel) groups and moderate expression was noticed in the S. platensis gel group. The chart describes the quantification of TNF-α positive staining as area percent, data were presented as means ± SD, and a significant difference was considered at p ˂ 0.05. Note: GpI/control negative (-ve): non-wounded rats; GpII/control positive (+ve): untreated wounded rats; GpIII/standard group: wounded rats treated with MEBO^®; GpIV/S. platensis gel: wounded rats treated with S. platensis gel; and GpV/nano-spirulina (SPNP)-gel: wounded rats treated with SPNP-gel. Number of asterisks “*” above the columns indicates strength of significance.