Changes in skin protein expression/contents of (A,A*) LC3BII/I, (B,B*) Beclin-1, (C) Caspase-3, and (D,D*) AIF due to application of standard, S. platensis gel and nano-S. platensis gel (SPNP-gel); A*, B*, and D* are the Western blot results for LC3BII/I, Beclin-1, and AIF, respectively. The values are presented as mean (n = 8) ± SD and a statistical analysis was carried out using a one-way ANOVA followed by Tukey’s post hoc multiple comparison test. As compared with control -ve (X), control +ve (Y), Standard (Z), S. platensis gel (ϕ); p < 0.05. Abbreviations: LC3B—light chain 3B and AIF—apoptosis-inducing factor. Note: GpI/control negative (-ve): non-wounded rats; GpII/control positive (+ve): untreated wounded rats; GpIII/standard group: wounded rats treated with MEBO®; GpIV/S. platensis gel: wounded rats treated with S. platensis gel; and GpV/nano-spirulina (SPNP)-gel: wounded rats treated with SPNP-gel.