Figure 11.

Photomicrograph of skin (immune staining) showing the VEGF expression at the wound area; control -ve showing negative expression of VEGF; control +ve group showing very limited negative VEGF staining; moderate VEGF expression was noticed in the S. platensis gel group; and marked increase in VEGF was noticed in the standard and nano-S. platensis gel (SPNP-gel) groups. The chart describes the quantification of VEGF positive staining as area percent, data were presented as means ± SD, and a significant difference was considered at p ˂ 0.05. Note: GpI/control negative (-ve): non-wounded rats; GpII/control positive (+ve): untreated wounded rats; GpIII/standard group: wounded rats treated with MEBO^®; GpIV/S. platensis gel: wounded rats treated with S. platensis gel; and GpV/nano-spirulina (SPNP)-gel: wounded rats treated with SPNP-gel. Number of asterisks “*” above the columns indicates strength of significance.