Table 4.
Composition of full factorial design of S. platensis nanophytosomes and the EE%, PS, PDI, ZP and Q6h results.
| Formula | PC (mg) | CH (mg) | EE (%) | PS (nm) | PDI | ZP (mV) | Q6h (%) |
|---|---|---|---|---|---|---|---|
| F1 | 50 | 0 | 37.81 ± 1.61 | 175.1 ± 0.77 | 0.43 ± 0.06 | −13.60 ± 0.57 | 89.00 ± 3.50 |
| F2 | 100 | 0 | 42.36 ± 6.04 | 206.36 ± 4.11 | 0.46 ± 0.06 | −11.66 ± 0.57 | 79.00 ± 2.90 |
| F3 | 50 | 50 | 51.19 ± 1.84 | 494.23 ± 48.05 | 0.69 ± 0.13 | −11.13 ± 0.20 | 80.00 ± 4.00 |
| F4 | 100 | 50 | 62.76 ± 1.75 | 598.40 ± 9.68 | 0.62 ± 0.07 | −19.80 ± 0.49 | 74.00 ± 1.90 |
Abbreviations: EE%—entrapment efficiency percent, CH—cholesterol, PS—particle size, PDI—polydispersity index, PC—phospholipid, ZP—zeta potential, and Q6h—percentage of drug released after 6 h.