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. 2023 Mar 2;15(3):810. doi: 10.3390/pharmaceutics15030810

Figure 9.

Figure 9

Targeting AGT promoted chemotherapy efficacy through inhibiting EMT in GC cells via the PI3K/AKT signaling pathway. (A,B) Images and quantified analysis of clone formation assay in HGC-27 and BGC-823 cells with Sh-AGT and 5-Fu. (C,D) Representative images and quantified analyses of Transwell assay in HGC-27 and BGC-823 cells with Sh-AGT and 5-Fu (2 × 104 cells, 48 h). (E,F) Representative data from Transwell assay performed in the indicated cells treated with or without 5-Fu or 740 Y-P (HGC-27 and BGC-823, 2 × 104 cells, 48 h). Scale bar = 100 μm. *** p < 0.001, ** p < 0.01.