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. 2023 Mar 20;24(6):5872. doi: 10.3390/ijms24065872

Figure 6.

Figure 6

Rocaglates influenced the surface marker expression of MdDCs. Primary human monocytes were differentiated to MdDCs for 5 days with GM-CSF (10 ng/mL) and IL-4 (10 ng/mL) in the presence or absence of rocaglates. Surface marker expression was measured with a MACSQuant® Analyzer 10. The geometric mean of the fluorescence intensity was related to vehicle control. Above the graphs, a representative histogram of the geometric mean fluorescence intensity is shown. N = 3–6. For statistical analysis, mixed-effect analysis with Dunnett’s multiple comparisons test was used. * p < 0.05, ** p < 0.01, and *** p < 0.001 indicate significant differences between rocaglate- and vehicle-treated samples. Abb.: unst., unstained.