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Rocaglates influenced the cytokines released by MdDCs. Primary human monocytes were differentiated to MdDCs for 5 days with GM-CSF (10 ng/mL) and IL-4 (10 ng/mL) in the presence or absence of rocaglates. Released cytokines were measured with a cytometric bead array. N = 3–6. For statistical analysis, mixed-effect analysis with Dunnett’s multiple comparisons test was used. *** p < 0.001 indicate significant differences between rocaglate- and vehicle-treated samples.
