Table 1.
Baseline characteristics of patients with COVID-19 hospitalized during Delta and Omicron waves with regard to RDV treatment.
| Delta | Omicron | p (between RDV-Treated Patients in Delta and Omicron Wave) | |||||
|---|---|---|---|---|---|---|---|
| RDV (n = 490) |
NO AVT (n = 680) |
p | RDV (n = 272) |
NO AVT (n = 380) |
p | ||
| Gender. females/males, % | 47.1/52.9 | 46.5/53.5 | >0.05 | 43.8/56.3 | 48.4/51.6 | >0.05 | >0.05 |
| Age (years), mean ± SD | 63.3 ± 17.1 | 65.1 ± 16.8 | >0.05 | 70.6 ± 17.2 | 68.4 ± 18.8 | >0.05 | <0.001 |
| BMI (kg/m2), mean ± SD | 28.7 ± 5.1 | 28.2 ± 5.1 | >0.05 | 27.2 ± 5.9 | 27.0 ± 5.3 | >0.05 | <0.001 |
| SpO2 | 89.0 (6.7) | 88.1 (8.1) | >0.05 | 91.7 (4.8) | 91.6 (6.3) | >0.05 | <0.001 |
| Comorbidities, % (n) | |||||||
| Any Comorbidity | 75.5 (370) | 77.2 (525) | >0.05 | 93.0 (253) | 92.1 (350) | >0.05 | <0.001 |
| Hypertension | 53.1 (260) | 50.9 (346) | >0.05 | 60.7 (165) | 52.9 (201) | 0.049 | 0.04 |
| Diabetes | 21.4 (105) | 19.7 (134) | >0.05 | 25.0 (68) | 25.3 (96) | >0.05 | >0.05 |
| Stroke | 3.1 (15) | 6.2 (42) | 0.015 | 12.5 (34) | 9.5 (36) | >0.05 | <0.001 |
| COPD | 4.5 (22) | 5.3 (36) | >0.05 | 7.7 (21) | 7.1 (27) | >0.05 | >0.05 |
| Neoplastic diseases | 7.6 (37) | 6.5 (44) | >0.05 | 13.2 (36) | 16.3 (62) | >0.05 | 0.0106 |
| Ischemic heart diseases | 9.4 (46) | 12.6 (86) | >0.05 | 23.5 (64) | 18.9 (72) | >0.05 | <0.001 |
| Other CVD | 19.2 (94) | 20.7 (141) | >0.05 | 33.1 (90) | 31.8 (121) | >0.05 | <0.001 |
| Other respiratory diseases | 8.2 (40) | 7.5 (51) | >0.05 | 11.8 (32) | 9.5 (36) | >0.05 | >0.05 |
| Other metabolic diseases | 10.6 (52) | 11.3 (77) | >0.05 | 16.2 (44) | 13.7 (52) | >0.05 | 0.03 |
| Others | 44.5 (218) | 47.6 (324) | >0.05 | 72.8 (198) | 70.8 (269) | >0.05 | <0.001 |
AVT, antiviral therapy; BMI, body mass index; COPD, chronic obstructive pulmonary disease; CVD, chronic vascular disease; RDV, remdesivir; SD, standard deviation; SpO2, saturation of peripheral oxygen.