Figure 8.
In vivo aerosol lung deposition. (left) Representative image of aerosol (AP-Phages + Tc99m-DTPA) deposition in intubated and mechanically ventilated non-human primates. The respiratory parameters were: 25 mL for tidal volume (Vt), 35 breaths per minute (bpm) for respiratory frequency (RF); an inspiratory: expiratory ratio of 1:2; 5 cm H2O for positive end expiratory pressure (PEEP). (right) Quantity of aerosol deposited in the lungs and endotracheal tube (ETT), and expressed as the percentage of the radiotracer quantity loaded in the nebulizer and given to each animal.