Table 1.

Binding kinetics of TXB2 and TXB4 to hTfR1 and mTfR1. To determine binding kinetic properties, a multicycle SPR analysis was performed using Biacore.

	hTfR1			mTfR1
	ka (1/Ms)	kd (1/s)	KD (M)	ka (1/Ms)	kd (1/s)	KD (M)
TXB2	7.2 × 104	5.2 × 10−4	7.2 × 10−9	2.5 × 105	1.6 × 10−4	6.5 × 10−10
TXB4	2.2 × 105	7.4 × 10−4	3.4 × 10−9	5.2 × 105	2.9 × 10−4	5.5 × 10−10