Table 6.

Summary of risk-of-bias assessment (QUADAS-2 tool). Green: low risk of bias or low concern in applicability. Orange: unclear risk. Red: high risk of bias or high concern in applicability. The assessment is weighted based on the sample size in each study.

	Risk of Bias					Applicability Concerns
	Patients Selection	Index Test	References Standard	Flow and Timing		Patients Selection	Index Test	References Standard
Al-Rawaf 2021 [26]
Baloun 2022 [27]
Bedene 2016 [28]
Chen 2016 [29]
Chen 2017 [30]
Chen 2019 [31]
Chen 2019 b [32]
Cheng 2019 [33]
Ciuffi 2022 [34]
Ding 2019 [35]
Feurer 2019 [36]
Fu 2019 [37]
Fu 2021 [38]
Gao 2020 [39]
Guo 2022 [40]
Ismail 2020 [41]
Li 2014 [42]
Li 2018 [43]
Li 2020 [44]
Lu 2021 [45]
Luo 2019 [46]
Lv 2019 [47]
Ma 2021 [48]
Ma 2022 [49]
Mandourah 2018 [50]
Mi 2020 [51]
Nakashima 2020 [52]
Nobrega 2020 [53]
Panach 2015 [54]
Pertusa 2021 [55]
Qiao 2019 [56]
Ramírez-Salazar 2019 [57]
Salman 2021 [58]
Seeliger 2014 59]
Shuai 2020 [60]
Sun 2020a [61]
Sun 2020b [62]
Tang 2019 [63]
Wang 2018 [64]
Weilner 2015 [65]
Wu 2021 [66]
Xia 2018 [67]
Xu 2022 [68]
Yang 2019 [69]
Yavropoulou 2017 [70]
Yin 2022 [71]
You 2016 [72]
Yu 2020 [73]
Yuan 2021 [74]
Zarecki 2020 [75]
Zhang 2019 [76]
Zhang 2021 [77]
Zhao 2019 [78]
Zhou 2019 [79]
He 2020 [80]
He 2021 [82]
Liu 2021 [82]
Valášková 2021 [83]