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. 2023 Mar 14;24(6):5536. doi: 10.3390/ijms24065536

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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NaA-regulated macrophage inflammatory response is related to AMPK activity. (A) HPLC was used to evaluate the intracellular AMP/ATP ratio. (B) Western blot was used to evaluate the phosphorylation of AMPK. (C) Inhibitory effect of Compound C on AMPK. (D) Western blot was used to evaluate the phosphorylation of c-Jun and p65 treated by Compound C. For all bar graphs, data are the mean ± SD, # p < 0.05, as compared with CON, and * p < 0.05, as compared with MOD. The significant difference was assessed using the one-way ANOVA followed by LSD post-tests. Control group (CON), group model cell treated with an LPS (MOD), 0.1 mM sodium acetate group (NaA-L), 2 mM sodium acetate group (NaA-H), arbitrary unit (AU).