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Micafungin plasma PK characteristics in neonates and young infants up to 6 months of age.
| 0 to ≤28 Days (n = 16) |
>28 Days ≤120 Days (n = 23) |
>120 Days (n = 13) |
|
|---|---|---|---|
| Clearance (L/h), mean ± SD | 0.072 ± 0.066 | 0.087 ± 0.049 | 0.109 ± 0.071 |
| Clearance/weight (L/h/kg), mean ± SD | 0.036 ± 0.016 | 0.036 ± 0.010 | 0.028 ± 0.011 |
| AUC (mg·h/L), mean ± SD | 259.0 ± 92.7 | 236.8 ± 63.9 | 346.4 ± 145.0 |
| Half-life (h), mean ± SD | 13.5 ± 7.6 | 13.4 ± 4.3 | 14.4 ± 4.2 |
