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. 2023 Mar 21;24(6):5927. doi: 10.3390/ijms24065927

Table 2.

Recommendation regarding the use of Lp(a) measurements in clinical practice.

Guidelines Recommendation
ESC/EAS (European Society of Cardiology/European Atherosclerosis Society) for the management of dyslipidemias [76]
  • Family history of premature cardiovascular disease

  • Once in the lifetime of each adult person

  • Moderate to high risk of cardiovascular event

HEART UK
(Hyperlipidaemia Education and Atherosclerosis Research Trust UK) [77]
  • Calcific aortic valve stenosis

  • Familial hypercholesterolaemia or other genetic forms of dyslipidaemia

  • First-degree relatives of those with high Lp(a) levels (>200 nmol/L)

  • Personal or family history of premature ASCVD (<60 years of age)

  • A borderline increased 10-year risk of cardiovascular events

AHA/ACC (American Heart Association/American College of Cardiology) Guideline of the Management of Blood Cholesterol
[78]
  • Personal or family history of premature ASCVD

NLA (National Lipid Association)
[79]
  • Premature ASCVD

  • Recurrent or progressive ASCVD

CCS (Canadian Cardiovascular Society)
[80]
  • Family history of premature coronary artery disease

  • Individuals with intermediate risk scores

ASCVD, atherosclerotic cardiovascular disease; Lp(a), lipoprotein (a).