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(A,B) Overall structure of the FGFR2 kinase domain in a complex with compound 38 (PDB code 7OZY). The N-lobe (blue) and C-lobe (pink), P-loop (orange), catalytic loop (marine), activation-loop (A-loop) (purple), hinge region (green), and compound 38 are highlighted. (C) Chemical structure of compound 38.
