Figure 3.

Incident flavivirus infection detected after initial decay of maternal-derived anti-ZIKV IgG in early life. Paired samples available from time points before and after the observed increase in anti-ZIKV IgG were selected for NAb testing. (A) Representative raw FRNT data measuring NAb to ZIKV (left) and DENV2 (right) are shown for three subjects. (B,C) eFRNT50 values for ZIKV (left) and DENV2 (right) are shown for suspected cases of incident flavivirus infection in Cohort 1 (B) and Cohort 2 (C). For nine samples with suspected incident flavivirus infection., and eFRNT50 values for paired samples are linked by a solid line.