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. 2023 Mar 5;15(3):847. doi: 10.3390/pharmaceutics15030847

Scheme 1.

Scheme 1

(A) Synthesis route of the DC-WCS-PG graft copolymer. (B) Radiolysis mechanism and radiation-induced grafting of PEGMA onto DC-WCS in aqueous solution. (C) Possible behavior of the radiation-induced grafting of PEGMA onto DC-WCS in (a) water and (b) an aqueous water/ethanol co-solvent. (D) DC-WCS-PG graft copolymer building block and its self-assembly into amphiphilic core–shell NPs in water. (E) PTX and BBR encapsulation in DC-WCS-PG NPs. (F) Possible drug release behavior at pH 6.5 and 7.4.