Skip to main content
. 2023 Mar 14;28(6):2621. doi: 10.3390/molecules28062621

Table 2.

Application of antibody phage display technology in antibacterial field.

Target Bacterial Strain Library Product Potential Application Time Reference
ICL MTB HuscFv library a-rICL-C6 Antimicrobial candidates 2022 [30]
LAM MTB Immunized rabbit scFv library Rabbit anti-LAM
IgG mAbs		 Detection of MTB 2021 [31]
OmpU V.
parahaemolyticus 		Human sdAb library UAb28 Antimicrobial candidates 2020 [32]
LAM MTB Immunized rabbit and chicken scFv library Three mAbs
(S4-20, G3, and TB)		 Detection of MTB 2019 [33]
SpuE P. aeruginosa HuscFv library ScFv5 Antimicrobial candidates 2019 [34]
ETA P. aeruginosa HuscFv library ETA bound-HuscFvs Antimicrobial candidates 2019 [35]
Flap region
of urease
enzyme		 H. pylori Human semi-synthetic antibody library VL antibody C3 Antimicrobial candidates 2019 [36]
Pep27 S. pneumoniae HuscFv library Two HuscFvs
(E2 and F9)		 Detection of
S. pneumoniae 		2018 [37]
PspA S. pneumoniae HuscFv library HuscFv 2B11 Detection of
S. pneumoniae 		2017 [38]
Pep90, penam sulfone
derivative		 ND Immunized mice scFv library P90C1, P90C2, P90C3,
PSC1 and PSC2		 Further information on the structure about β-lactamase catalytic function 2017 [39]
S. aureus S. aureus HuscFv library ScFv-Fcs
(S78, S117)		 Antimicrobial candidates 2016 [40]
S. aureus S. aureu Immunized chicken T7 scFv
antibody library		 SFV6 Antimicrobial candidates 2016 [41]
MrkA K. pneumoniae HuscFv library IgG1
(KP3, KP16)		 Antimicrobial candidates 2016 [42]
S. aureus
soluble whole-cell
antigen		 S. aureus Immunized cows bovine scFv library 8 anti-
S. aureus scFvs		 Antimicrobial candidates 2016 [43]
VIM-4 MβL ND Immunized llama and dromedary nanobody
library		 NbVIM_38
nanobody		 Antimicrobial candidates 2013 [14]

Abbreviations: ND, Not detect.