TABLE 3.
Sensitivity analyses
| Studies/patients n | Risk ratio (95% CI), I2 (%) |
Haemodynamically stable patients only
risk ratio (95% CI), I2 (%) |
|
| RVD | |||
| Number of criteria for RVD definition: | |||
|
≥1 echo criterion ≥2 echo criteria ≥3 echo criteria |
16/5488 7/2633 1/89 | 1.50 (1.28–1.87), 24 1.76 (1.46–2.12), 0 0.44 (0.30–0.65)# | 1.52 (1.15–2.00), 73 |
| Studies including >100 patients | 16/7502 | 1.59 (1.36–1.87), 36 | - |
| Studies published beyond 2010 | 12/6318 | 1.47 (1.24–1.74), 33 | - |
| RV/LV | |||
| Different cut-offs: | |||
| ≥1 | 9/2079 | 1.57 (0.93–2.65), 35 | 1.11 (0.91–1.35), 0 |
| >1 | 2/990 | 1.09 (0.91–1.35), 0 | |
| >0.6 | 1/950 | 3.47 (1.72–6.98)# | |
| TAPSE | |||
| Different cut-offs: | |||
| ≥15 mm | 3/828 | 3.23 (1.45–7.18), 0 | 2.29 (0.97–5.44), 71 |
| >16 mm | 6/1159 | 2.19 (0.80–6.03), 66 | |
| >20 mm | 1/2108 | 1.68 (0.78–3.64), 0 |
CI: confidence interval; RVD: right ventricular dysfunction as comprehensive definition; RV/LV ratio: right ventricle/left ventricle diameter ratio; TAPSE: tricuspid annular plane systolic excursion. #: the result is obtained for one study only, thus I2 is not calculated.