Table 2.

Characteristics of the included studies

First author (year)	Location	Study design	Health status	Gender	Sample size	Duration (week)	Mean age (year)	Baseline BMI (kg/m2)	Intervention		Outcome
									Treatment group	Control group
Cesara (2010) (a)	Brazil	Randomised, placebo-controlled, parallel trial	hypercholesterolaemic	Both	22	8	43·15	26	750 ml orange juice	Placebo	TC/TG/LDL/HDL
Cesara (2010) (b)	Brazil	Randomised, placebo-controlled, parallel trial	Normorcholesterolaemic	Both	39	8	39·9	27·2	750 ml orange juice	Placebo	TC/TG/LDL/HDL
Aptekmann (2010)	Brazil	Randomised, placebo-controlled, parallel trial	Overweight	Female	26	12	39	28·7	500 ml orange juice	Placebo	TC/TG/LDL/HDL
Morand (2010)	France	Randomised, double-blind, placebo-controlled, cross-over	Overweight	Male	24	4	56	27·4	500 ml orange juice	Placebo	TC/TG/LDL/HDL
Asgary (2014)	Iran	Randomised, single-blind, placebo-controlled, cross-over	Healthy	Both	21	4	35·13	24·5	1000 ml orange juice	Placebo	TC/TG/LDL/HDL
Constans (2014)	France	Randomised, single-blind, placebo-controlled, cross-over	Hypercholesterolaemic	Male	25	3	53·8	26	600 ml orange juice	Placebo	TC/TG/LDL/HDL
Simpson (2016)	UK	Randomised, single-blind, placebo-controlled, parallel trial	Overweight	Male	36	12	48·3	31	250 ml orange juice	Placebo	TC/TG/LDL/HDL
Ribeiro (2016)	Brazil	Randomised, non-blind, placebo-controlled, parallel trial	Obese	Both	78	12	36	33	500 ml orange juice and reduced-calorie diet	Reduced-calorie diet	TC/TG/LDL/HDL
Gonçalves (2017)	Brazil	Randomised, placebo-controlled, parallel trial	Patients with hepatitis C	Both	43	8	18<	23·9	500 ml orange juice	Placebo	TC/TG/LDL/HDL
Ponce (2019)	Brazil	Randomised, non-blind, placebo-controlled, parallel trial	MetS	Both	72	12	48	34·6	500 ml orange juice and nutritional guidance	Placebo and nutritional guidance	TC/TG/LDL/HDL

TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TG, triglycerides; MetS, metabolic syndrome.