Table 3.

Subgroup analysis of included randomised controlled trials in meta-analysis of the effect of orange juice on lipid profile

Group	No. of trials	WMD (95 % CI)	P-valuea	I2 (%)b	P-heterogeneityc	P for between subgroup heterogeneityd
TC
Dosage (ml/d)						0·259
≤500	6	−6·92 (−14·55, 0·70)	0·075	81·5	<0·001
>500	3	−6·61 (−31·78, 18·57)	0·607	88·5	<0·001
Duration (week)						0·002
≤8	2	−6·40 (−18·29, 5·49)	0·291	87·2	<0·001
>8	4	−6·83 (−15·03, 1·37)	0·102	48·4	0·121
Gender						<0·001
Both	5	−12·75 (−20·19, −5·31)	0·001	50·4	0·073
Male	3	6·09 (−10·22, 22·41)	0·464	88·3	<0·001
Female	1	−5·20 (−19·05, 8·65)	0·462	–	–
LDL
Dosage (ml/d)						0·012
≤500	6	−7·44 (−16·82, 1·93)	0·120	89·9	<0·001
>500	3	−9·85 (−18·18, −1·52)	0·020	19·4	0·293
Duration (week)						<0·001
≤8	5	−7·91 (−15·91, −0·36)	0·040	72·0	0·003
>8	4	−7·99 (−22·43, 6·44)	0·278	86·0	<0·001
Gender						<0·001
Both	5	−12·61 (−21·19, −4·04)	0·004	68·9	0·007
Male	3	−0·77 (−6·18, 4·63)	0·779	38·1	0·199
Female	1	−10·30 (−25·40, 4·80)	0·181	–	–
HDL
Dosage (ml/d)						0·232
≤500	6	0·47 (−0·91, 1·84)	0·506	86·5	<0·001
>500	3	1·56 (−1·07, 4·19)	0·245	0·0	0·635
Duration (week)						0·300
≤8	5	−0·39 (−2·63, 1·85)	0·733	56·8	0·041
>8	4	3·22 (−0·61, 7·05)	0·099	89·1	<0·001
Gender						<0·001
Both	5	0·20 (−2·80, 3·19)	0·898	66·9	0·010
Male	1	−0·20 (−1·02, 0·61)	0·624	–	–
Female	2	12·10 (6·37, 17·83)	<0·001	73·1	0·024

WMD, weighted mean difference; CI, confidence interval; TC, total cholesterol; TG, triglycerides; HDL, high-density lipoprotein; LDL, low-density lipoprotein.

^aRefers to the mean (95 % CI).

^bInconsistency, percentage of variation across studies due to heterogeneity.

^cObtained from the Q-test.

^dObtained from the fixed-effects model.