Figure 4.

Comparative genomic analysis of 376 genomes E. faecalis genomes across the One Health continuum. (A) Circos plot depicts the relationship between commonly found ARGs and One Health sectors. The variables (ARGs and genome isolation source) are arranged around the circle and distinguished by different colors. The percentage of ARGs across various sectors is indicated by proportional bars (http://circos.ca/). (B) Maximum likelihood core-genome phylogenetic tree. E. faecalis ATCC 47077/OG1RF (CP002621.1) was used as the reference genome. Genomes were characterized based on their source of isolation into four groups: livestock, clinical, municipal wastewater, and environmental.