Table 1.

Studies focusing on the protective effects of yellow-tinted IOLs upon the retina.

Year	Title	Authors	Subjects (Eyes with Yellow/Clear IOL)	Element of Study	Primary Endpoint	Type of Study	Maximum Follow-Up	Outcome
2010	Comparison of visual performance with blue light-filtering and ultraviolet light-filtering intraocular lenses	Neumaier-Ammerer et al. [41]	76 (37/39)	Cones and rods	VA, CS, Color vision	Prospective, randomized, double-blind control trial	2 months	Negative: no difference between tested parameters (except for color vision)
2011	Effects of blue light-filtering intraocular lenses on the macula, contrast sensitivity, and color vision after a long-term follow-up	Kara-Junior et al. [42]	25 (25/25)	Cones and rods	CS, Color vision, OCT Ophthalmoscopy	Prospective randomized control trial	5 years	Negative: no differences between tested parameters
2015	Prevention of increased abnormal fundus autofluorescence with blue light-filtering intraocular lenses	Nagai et al. [43]	131 (52/79)	RPE cells	FAF	Prospective comparative observational study	2 years	Positive: Lower FAF abnormalities and AMD incidence in the yellow-tinted IOL group
2015	Color of Intra-Ocular Lens and Cataract Type Are Prognostic Determinants of Health Indices After Visual and Photoreceptive Restoration by Surgery	Ayaki et al. [44]	206 (135/71)	Cones and rods	Japanese versions of: VFQ-25 PSQI	Prospective comparative observational study	7 months	Positive: improvement of VFQ-25 (yellow-tinted IOL) and PSQI (clear IOL)
2016	Effect of blue light-filtering intraocular lens on color vision in patients with macular diseases after vitrectomy	Mokuno et al. [45]	67 (27/40)	Cones and rods	Color vision	Prospective comparative observational study	16 months	Negative: no differences between study groups

VA = visual acuity; CS = contrast sensitivity; OCT = optical coherence tomography; FAF = fundus autofluorescence; VFQ-25 = National Eye Institute Visual Function Questionnaire; PSQI = Pittsburg Sleep Quality Index.